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GSFL - Publications2009
2008
2007 2006 Stamp, L., Roberts, R., Kennedy, M., Barclay, M., O’Donnell, J., Chapman, P. (2006) The use of low dose methotrexate in rheumatoid arthritis – are we entering a new era of therapeutic drug monitoring and pharmacogenomics? Biomedicine and Pharmacotherapy 60, 678-87. Light, K., Joyce P.R., Luty, S., Mulder, R., Frampton, C., Joyce, L., Miller, A.L., Kennedy, M.A. (2006). Preliminary evidence for an association between a dopamine D3 receptor gene variant and obsessive-compulsive personality disorder in patients with major depression American J. Medical Genet. 141B:409–413. Joyce, P. R., McHugh, P. C., McKenzie, J. M., Sullivan, P. F., Mulder, R. T., Luty, S. E., Carter, J. D., Frampton, C. M. A., Cloninger, C. R., Miller, A. M. & Kennedy, M. A. (2006) A dopamine transporter polymorphism is a risk factor for borderline personality disorder in depressed patients. Psychological Medicine. 36, 807-814. Gearry, R.B., Lea, R.A., Roberts, R.L., Chambers, G.K., Barclay, M.L., Kennedy, M.A. (2006) CARD15 allele frequency differences in New Zealand Maori: ancestry-specific susceptibility to Crohn's disease in New Zealand? Gut 55, 580. Roberts, R.L., Kennedy, M.A. (2006) Rapid detection of common Cytochrome P450 2D6 alleles in Caucasians. Clinica Chimica Acta 366, 348 - 351. Joyce P.R., McKenzie J.M., Mulder R.T., Luty S.E., Sullivan P.F., Miller A.L., Kennedy M.A. (2006) Genetic, developmental and personality correlates of self mutilation in depressed patients. ANZ. J. Psychiatry 40, 225–229. 2005 Taylor, D.R., Epton, M., Kennedy, M.A., Smith, A.D., Isles, S., Miller, A.L., Littlejohn, M.D., Cowan, J.O., Hewitt, T., Swanney, M.P., Brassett, K.P., Herbison, G.P. (2005) Bronchodilator response in relation to beta-adrenoceptor haplotype in patients with asthma.. Amer. J. Resp. Crit. Care Med. 172, 700-703. Kennedy MA, Roberts RL, Joyce PR (2005) Re: No evidence of increased adverse drug reactions in cytochrome P450CYP2D6 poor metabolizers treated with fluoxetine or nortriptyline - Authors' response. Hum Psychopharmacol Clin Exp 20 (1): 63-64. Joyce, P. R., Porter, R. J., Mulder, R. T., Luty, S. E., McKenzie, J. M., Miller, A. L., and Kennedy, M. A. (2005). Reversed diurnal variation in depression: associations with a differential antidepressant response, tryptophan: large neutral amino acid ratio and serotonin transporter polymorphisms. Psychol Med 35, 511-517. 2004 Gearry, R.B., Roberts, R.L., Barclay, M.L., Kennedy, M.A. (2004) Lack of association between the ITPA 94C>A polymorphism and adverse effects from azathioprine. Pharmacogenetics 14, 779-781. Clark, D.W.J., Donnelly, E., Coulter, D.M., Roberts, R.L., Kennedy, M.A. (2004) Linking Pharmacovigilance with Pharmacogenetics. Drug Safety 27(15) 1171-1184. Roberts, R.L., Gearry, R.B, Barclay, M.L., Kennedy, M.A. (2004) Rapid detection of common CARD15 variants in patients with inflammatory bowel disease. Molecular Diagnosis 8(2) 101-105. Roberts, R.L., Luty, S.E., Mulder, R.L., Joyce, P.R., Kennedy, M.A.. (2004) Association between Cytochrome P450 2D6 genotype and Harm Avoidance. Amer. J Med. Genet. 127B:90-93. Rogers, G., Joyce, P., Mulder, R., Sellman, D., Miller, A., Allington, M., Olds, R., Wells, E., Kennedy, M. (2004) Association of a duplicated repeat polymorphism in the 5'-untranslated region of the DRD4 gene with novelty seeking. Amer. J. Med. Genet. 126B:95-98. Roberts, R.L., Barclay, M.L., Gearry, R., Kennedy, M.A. (2004). A multiplexed allele-specific polymerase chain reaction assay for the detection of common thiopurine methyltransferase (TPMT) mutations. Clinica Chimica Acta 341, 49-53. Roberts, R.L., Mulder, R.T., Joyce, P.R., Luty, S.E., Kennedy, M.A. (2004) No evidence of increased side effects in cytochrome P450 2D6 poor metabolisers treated with either fluoxetine or nortriptyline. Hum Psychopharmacol Clin Exp 19, 17–23. 2003 Joyce, P.R., Mulder, R.T., Luty, S.E., McKenzie, J.M., Miller, A.L., Rogers, G.R., Kennedy, M.A. (2003) Age dependent antidepressant pharmacogenomics: polymorphisms of the serotonin transporter and G protein ?3 subunit as predictors of response to fluoxetine and nortriptyline. Int. J. Neuropsychopharm. 6, 339 – 346. Barclay, M.L., Sawyer, S.M., Begg, E.J., Zhang, M., Roberts, R.L., Kennedy, M.A., Elliot, J. (2003) Correlation of CYP450 2D6 genotype with perhexiline phenotypic metabolizer status. Pharmacogenetics 13, 627-632. Gearry RB, Barclay ML, Burt MJ, Collett JA, Chapman BA, Roberts RL, Kennedy MA. (2003) Thiopurine S-methyltransferase (TPMT) genotype does not predict adverse drug reactions to thiopurine drugs in patients with inflammatory bowel disease. Aliment Pharmacol Ther 18, 395-400. Joyce, P.R., Rogers, G.R., Miller, A.L., Mulder, R.T., Luty, S.E., Kennedy, M.A. (2003). Polymorphisms of DRD4 and DRD3 and risk of avoidant and obsessive personality traits and disorders. Psychiatry Res. 119, 1-10. Sundram, S., Joyce, P.R., Kennedy, M.A. (2003) The nature and neurobiology of schizophrenia and bipolar affective disorder. Current Molecular Medicine 3, 393-407. 2002 Littlejohn, M.L., Taylor, D.R., Miller, A.M., Kennedy, M.A. (2002) Determination of ?2-adrenergic receptor haplotypes by a multiplexed polymerase chain reaction assay. Human Mutation 20, 479-479, Mutation in Brief #562 Online. Roberts, R.L., Joyce, P.R., Mulder, R.T., Begg, E.J., Kennedy, M.A. (2002) A common P-glycoprotein polymorphism is associated with nortriptyline-induced postural hypotension in patients treated for major depression. Pharmacogenomics Journal 2, 191-196. Stedman, C.A.M., Begg, E., Kennedy, M.A., Roberts, R., Wilkinson, T.J. (2002) Cytochrome P450 2D6 genotype does not predict SSRI (fluoxetine or paroxetine) induced hyponatraemia. Hum Psychopharmacol Clin Exp 2002 17, 187–190. Wood, J.G., Joyce, P.R., Miller, A.L., Mulder, R.T., Kennedy, M.A. (2002) A polymorphism in the dopamine ?-hydroxylase gene is associated with “paranoid ideation” in patients with major depression. Biological Psychiatry 51, 365-369. Roberts, R.L., Begg, E.J., Joyce, P.R., Kennedy, M.A. (2002). How the pharmacogenetics of cytochrome P450 enzymes may affect prescribing. NZ Med. J 115, 137-140. Ferguson, G.C., Heinemann, J.A., Kennedy, M.A. (2002) Gene transfer between Salmonella enterica Serovar Typhimurium inside epithelial cells. J. Bacteriology 184, 2235-2242. Taylor, D.R., Kennedy, M.A. (2002) Beta-adrenergic receptor polymorphisms and drug responses in asthmatics. Pharmacogenomics 3, 173-184. 2001 Taylor, D.R., Kennedy, M.A. (2001) Genetic variation of the ?2 adrenoceptor: its functional and clinical importance in bronchial asthma. Amer. J. Pharmacogenomics 1, 165-174. Martin, J.H., Begg, E.J., Kennedy, M.A., Roberts, R., Barclay, M.L. (2001) Is cytochrome P450 2C9 genotype associated with NSAID gastric ulceration? Brit J Clin Pharm 51, 627-630. Kennedy, M.A. (2001). What does the human genome project mean for medicine? NZ Med J 114, 190-192. 2000 Roberts, R., Sullivan, P., Joyce, P., Kennedy, M.A. (2000). Rapid and comprehensive determination of cytochrome P450 CYP2D6 poor metabolizer genotypes by multiplex polymerase chain reaction. Human Mutation. 16, 77-85. 1999 Hanrahan, V., George, P.M., Kennedy, M. (1999). Instability characteristics of trinucleotide (CAG) repeat tracts in Escherichia coli. J. Biochem. Molec. Biol. Biophys. 3, 117-125. 1998 Sullivan, P.F., Fifield, W.J., Kennedy, M.A., Mulder, R.T., Sellman, J.D., Joyce, P.R. (1998). No association between novelty seeking and the type 4 dopamine receptor (DRD4) in two New Zealand samples. American Journal of Psychiatry 155, 98-101. 1997 Sullivan PF, Fifield WJ, Kennedy MA, Mulder RT, Sellman JD, Joyce PR. (1997). Novelty seeking and a dopamine transporter gene polymorphism (DAT1). Biological Psychiatry 42, 1070-1072. Dodd, A., Rowland, S.A., Hawkes, S.L.J., Kennedy, M.A., Love, D.R. (1997). Mutations in the adrenoleukodystrophy gene. Human Mutation. 9, 500-511. 1996 Rowland SA., Dodd, A., Roche, AL., Manilal, S., Kennedy, MA., Becroft, DMO., Tonkin, S., Chapman, C., and Love, DR.(1996) DNA-based diagnostics for adrenoleukodystrophy in a large New Zealand family. NZ Med. J. 109, 312-315. Cameron, V.A., Aitken, G.D., Ellmers, L.J., Kennedy, M.A., Espiner, E.A. (1996). The sites of gene expression of Atrial, Brain and C-type natriuretic peptides in mouse fetal development: temporal changes in embryos and placenta. Endocrinology 137, 817-824. Kennedy, M.A., Rowland, S., Miller, A.L., Morris, C.M., Neville, L.A., Dodd, A., Fifield, W.J., Love, D.R. (1996) Structure and location of the murine adrenoleukodystrophy gene. Genomics 32, 395-400. Morris, C., Jeffs, A., Smith, T., McDonald, M., Board, P., Kennedy, M., Fitzgerald, P. (1996) BCR gene recombines with genomically distinct sites on band 11q13 in complex BCR-ABL translocations of chronic myeloid leukemia. Oncogene 12, 677-685. 1995 Neville, L., Cochrane, J., Fitzgerald, P., Kennedy, M. (1995). Fragile X mental retardation syndrome: DNA diagnosis and carrier detection in New Zealand families. NZ Med. J. 108, 190-192. 1994 Kennedy, M.A., Rayner, J.C., Morris, C.M. (1994). Genomic structure, promoter sequence and revised translation of human homeobox gene HLX1. Genomics 22, 348-355. Sander, A., Kennedy, M..A., Rayner, J.C., Murray, J.C. (1994). Dinucleotide repeat polymorphism for HLX1gene. Hum. Mol. Gen. 3, 219. 1993 Crossen, P.E., Kennedy, M.A., Heaton, D.C., Morrison, M.J. (1993) Cloning and sequencing of a t(14;19) breakpoint that involves the Cu switch region. Genes Chrom. Cancer 8, 60-62. Sowerby, S., Kennedy, M.A., Fitzgerald, P.H., Morris, C.M. (1993). DNA sequence analysis of the major breakpoint cluster region of the BCR gene rearranged in Philadelphia positive human leukemia. Oncogene 8, 1679-1683. 1991 Morris, C.M., Kennedy, M.A., Heisterkamp, N., Columbano-Green, L., Romeril, K., Groffen, J., Fitzgerald, P. (1991). A complex chromosome rearrangement forms the BCR-ABL fusion gene in leukemic cells with a normal karyotype. Genes Chrom. Cancer 3, 263-271. Kennedy, M.A., Gonzales-Sarmiento, R., Kees, U.R., Lampert, F., Dear, N., Boehm, T. Rabbitts, T.H. (1991). HOX-11, a homeobox-containing T-cell oncogene on human chromosome 10q24. Proc. Natl. Acad. Sci. USA. 88, 8900-8904. Kennedy, M.A. (1991). Novel chromosome translocation caused by fusion of immunoglobulin heavy and light chain V genes in a human B-lymphoblastoid cell line. J. Exp. Med. 173, 1033-1036. Boehm, T., Gonzales-Sarmiento, R., Kennedy, M.A., Rabbitts, T.H. (1991). A simple technique for generating probes for RNA in situ hybridization: an adjunct to genome mapping exemplified by the RAG-1/RAG-2 gene cluster. Proc. Natl. Acad. Sci. USA. 88, 3927-3931. 1990 Morris, C.M., Heisterkamp, N., Kennedy, M.A., Fitzgerald, P.H., Groffen, J. (1990). Ph-negative chronic myeloid leukemia: molecular analysis of ABL insertion into M-BCR on chromosome 22. Blood 76, 1812-1818. Boehm, T., Foroni, L., Kennedy, M.A., Rabbitts, T.H. (1990). The rhombotin gene belongs to a class of transcriptional regulators with a potential novel protein dimerisation motif. Oncogene 5, 1103-1105. 1989 Morris, C.M., Fitzgerald P.H., Kennedy, M.A., Hollings, P.E., Garry, M., Corbett, G.M. (1989). HRAS1 and INS genes are relocated but not structurally altered as a result of the t(7;11)(p15;p15) in a clone from a patient with acute myeloid leukemia (M4). Brit. J. Haematology 71, 481-486. Kennedy, M.A., Morris, C.M., Hollings, P.E., Fitzgerald, P.H. (1989). Involvement of immunoglobulin heavy- and light- chain (k) gene clusters in a human B-cell translocation, t(2;14). Cytogen. Cell Genet. 52, 50-56. Kennedy, M.A., Morris, C.M., Fitzgerald, P.H. (1989). A sequence homologous to kappa-deleting element is located 5' to the human Jk locus. Nucl. Acids Res. 17, 809. Kennedy, M.A., Morris, C.M., Fitzgerald, P.H. (1989). The oncogene ETS1 is distant from the chromosome 11 breakpoint in leukemic cells with the t(11;19)(q23;p13). Leukemia Res. 13, 459-463. Kennedy, M.A., Crossen, P.E. (1989). Nucleotide sequence of an immunoglobulin-D immunoglobulin-J gene fusion from a B-cell prolymphocytic leukaemia. Nucl. Acids Res. 17, 4879. Bodger, M.P., Morris, C.M., Kennedy, M.A., Bowen, J.A., Hilton, J.M., Fitzgerald, P.H. (1989). Basophils (Bsp-1+) derive from the leukemic clone in human myeloid leukemias involving the chromosome breakpoint 9q34. Blood 73, 777-781. 1988 Kennedy, M.A., Lane, D., Chandler, M. (1988). Mapping and regulation of the pifC promoter of the F plasmid. Biochim. Biophys. Acta 90, 75-80. Bosma, TJ., Kennedy, M.A., Bodger, M., Hollings, P., Fitzgerald, P. (1988). Basophils exhibit rearrangement of the bcr gene in Philadelphia chromosome positive chronic myeloid leukemia. Leukemia 2, 141-143. 1986 Lane, D., DeFeyter, R., Kennedy, M., Phua, S.H., Semon, D. (1986). D protein of mini-F plasmid acts as a repressor of transcription and as a site-specific resolvase. Nucl. Acids Res. 14, 9713-9728.
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Glubb, D.M., McHugh, P.C., Deng, S., Joyce,P.R., Kennedy, M.A.
(2009) Association of a functional polymorphism in the adrenomedullin
gene (ADM) with response to paroxetine. Pharmacogenomics Journal (Accepted)