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Free Radical Research
Group - Our People
Prof. Christine Winterbourn
MSc (Auckland), PhD (Massey)
ONZM, FRSNZ
Email christine.winterbourn@otago.ac.nz
Professor Christine Winterbourn FRSNZ ONZM is an Auckland University
chemistry graduate who received her PhD in biochemistry from Massey University
and did postdoctoral work at the University of British Columbia, Canada
before returning to the Pathology Department, University of Otago, Christchurch.
Where she now has a personal chair. She is Director of the Free Radical
Research Group and is supported financially by the Health Research Council
of New Zealand, the Marsden Fund and the National Research Centre for
Growth and Development. Professor Winterbourn has published more than
250 scientific papers. She has received the NZ Association of Scientists’ Marsden
Medal, Massey University 75th Anniversary Medal, Society for Free Radical
Research (Australasia) Distinguished Service Award, University of Otago
Distinguished Research Medal and Society for Free Radical Research (International)
Trevor Slater Award. She is a past member of the Health research Council
and Marsden Fund Council, and is an editor of the Biochemical Journal
and on the editorial board of Free Radical Biology and Medicine.
My field of research is the biological chemistry of free radicals and
other reactive oxidants and their involvement in health and disease.
My focus is on understanding mechanisms of reactive oxidant production,
the biochemistry of biological damage and the consequences for disease
pathology. My interests include the biochemistry of superoxide and the
role of superoxide dismutase in antioxidant defence; the production of
reactive oxidants by neutrophils and the enzymology of myeloperoxidase;
molecular and cellular targets for hypochlorous acid and chloramines
and their role in inflammation; thiol proteins, redox regulation and
the role of peroxiredoxins development and application of specific biomarkers
of oxidative stress; free radical reactions of haemoglobin and oxidative
stress in the red blood cell; oxidative stress and inflammation in chronic
lung injury in premature infants.
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