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CCERG - Biochemistry and Cell Biology

Selected Publications

  1. Smith MW, Espiner EA, Yandle TG, Charles CJ, Richards AM. Delayed metabolism of human brain natriuretic peptide reflects resistance to neutral endopeptidase. Journal of Endocrinology 2000;167:239-246.
  2. Yandle T, Fisher S, Espiner E, Richards M, Nicholls G. Validating aminoterminal BNP assays: a word of caution. Lancet 1999;353(9158):1068-1069.
  3. Lewis LK, Smith MW, Yandle TG, Richards AM, Nicholls MG. Adrenomedullin(1-52) measured in human plasma by radioimmunoassay -plasma concentration, adsorption, and storage. Clinical Chemistry 1998;44(3):571-577.
  4. Pemberton CJ, Yandle TG, Rademaker MT, Charles CJ, Aitken GD, Espiner EA. Amino-terminal probnp in ovine plasma - evidence for enhanced secretion in response to cardiac overload. American Journal of Physiology - Heart and Circulatory Physiology 1998;44(4):H1200-H1208.
  5. Hunt PJ, Espiner EA, Nicholls MG, Richards AM, Yandle TG. The role of the circulation in processing pro-brain natriuretic peptide (proBNP) to amino-terminal BNP and BNP-32. Peptides 1997;18(10):1475-1481.
  6. Hunt PJ, Richards AM, Nicholls MG, Yandle TG, Doughty RN, Espiner EA. Immunoreactive amino-terminal pro-brain natriuretic peptide (NT-proBNP) -a new marker of cardiac impairment. Clinical Endocrinology 1997;47(3):287-296.
  7. Lewis LK, Smith MW, Brennan SO, Yandle TG, Richards AM, Nicholls MG. Degradation of human adrenomedullin(1-52) by plasma membrane enzymes and identification of metabolites. Peptides 1997;18(5):733-739.
  8. Pemberton CJ, Yandle TG, Charles CJ, Rademaker MT, Aitken GD, Espiner EA. Ovine brain natriuretic peptide in cardiac tissues and plasma - effects of cardiac hypertrophy and heart failure on tissue concentration and molecular forms. Journal of Endocrinology 1997;155(3):541-550.
  9. Hunt PJ, Yandle TG, Nicholls MG, Richards AM, Espiner EA. The amino-terminal portion of pro-brain natriuretic peptide (pro-BNP) circulates in human plasma. Biochemical and Biophysical Research Communications 1995;214(3):1175-1183.

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Blood pressure and heart failure research