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Cancer Genetics Research
Group - Dr Ruth Spearing
Publications
Ganly, P.S., Keeman, H., Spearing, R.L., Smith, M.P.,
Patton, N., Merriman, E.G. & Gibbons, S.S. Written advice can provide
a safe and acceptable alternative to new patient assessment for selected
referrals to haematologists. Med
J Aust 188, 9-12 (2008).
Wilson, C., Spearing, R., Teague, L., Robertson, P. & Blacklock,
H. The outcome of clinical parameters in adults with severe Type I Gaucher
disease using very low dose enzyme replacement therapy. Mol Genet
Metab 92, 131-6 (2007).
Brune, M., Castaigne, S., Catalano, J., Gehlsen, K., Ho, A.D., Hofmann,
W.K., Hogge, D.E., Nilsson, B., Or, R., Romero, A.I., Rowe, J.M., Simonsson,
B., Spearing, R., Stadtmauer, E.A., Szer, J., Wallhult, E. & Hellstrand,
K. Improved leukemia-free survival after postconsolidation immunotherapy
with histamine dihydrochloride and interleukin-2 in acute myeloid leukemia:
results of a randomized phase 3 trial. Blood 108, 88-96 (2006).
Nieto, Y., Patton, N., Hawkins, T., Spearing, R., Bearman, S.I., Jones,
R.B., Shpall, E.J., Rabinovitch, R., Zeng, C., Baron, A. & McSweeney,
P.A. Tacrolimus and mycophenolate mofetil after nonmyeloablative matched-sibling
donor allogeneic stem-cell transplantations conditioned with fludarabine
and low-dose total body irradiation. Biol Blood Marrow Transplant 12,
217-25 (2006).
Ganly, P. & Spearing, R. Treatment with intravenous immunoglobulin
is not a panacea but should be limited to those who can benefit. NZ
Med J 119, U2335 (2006).
Chee, L., Spearing, R.L., Morris, C.M., McDonald, M., Hanrahan, V.,
Ebbett, A., Scott, R., Florkowski, C., Walmsley, T. & Patton, W.N.
Acquired myeloma-associated Type III hyperlipidaemia treated by nonmyeloablative
HLA-identical sibling allogeneic stem cell transplant using a donor with
essential thrombocythaemia (ET): evidence of engraftment without manifestation
of ET in recipient. Bone Marrow Transplant 35, 1213-4 (2005).
Chambers ST, Sanders J, Patton WN, Ganly P, Birch M, Crump JA, Spearing
RL. Reduction of exit-site infections of tunnelled intravascular catheters
among neutropenic patients by sustained-release chlorhexidine dressings:
results from a prospective randomized controlled trial. J Hosp Infect.
61, 53-61 (2005)
Ganly, P., McDonald, M., Spearing, R. & Morris, C.M. Constitutional
t(5;7)(q11;p15) rearranged to acquire monosomy 7q and trisomy 1q in a
patient with myelodysplastic syndrome transforming to acute myelocytic
leukemia. Cancer Genet Cytogenet 149, 125-30 (2004).
Hidajat, R.R., McLay, J.L., Goode, D.H. & Spearing, R.L. EOG as
a monitor of desferrioxamine retinal toxicity. Doc Ophthalmol.
109, 273-8 (2004).
Maghzal, G.J., Brennan, S.O., Fellowes, A.P., Spearing, R. & George,
P.M. Familial hypofibrinogenaemia associated with heterozygous substitution
of a conserved arginine residue; Bbeta255 Arg-->His (Fibrinogen Merivale). Biochim
Biophys Acta 1645, 146-51 (2003).
Walker, L.C., Stevens, J., Campbell, H., Corbett, R., Spearing, R., Heaton,
D., Macdonald, D.H., Morris, C.M. & Ganly, P. A novel inherited mutation
of the transcription factor RUNX1 causes thrombocytopenia and may predispose
to acute myeloid leukaemia. Br J Haematol 117, 878-81 (2002).
Hughes, M.J., Davis, F.M., Mark, S.D. & Spearing, R.L. Hyperbaric oxygen
for cyclophosphamide-induced cystitis. Br J Haematol 119, 575 (2002).
Beard, M.E.J., Potter, H.C., Spearing, R.L. & Brennan, S.O. Haemoglobin
Pierre-Benite, a high affinity variant associated with relative polycythaemia. Clin
Lab Haem 23, 407-409 (2001).
Stevens, J.M., Patton, W.N., Heaton, D.C., Spearing, R.L., Shaw, G., Bowie,
D., Smyth, D. & Comenzo, R. Autologous PBSCT in patients with cardiac amyloidosis. Bone
Marrow Transplant 26, 588-9 (2000).
Snowden, J.A., Hill, G.R., Hunt, P., Carnoutsos, S., Spearing, R.L., Espiner,
E. & Hart, D.N. Assessment of cardiotoxicity during haemopoietic stem cell
transplantation with plasma brain natriuretic peptide. Bone Marrow Transplant 26,
309-13 (2000).
Llewellyn, I.E., Morris, C.M., Stanworth, S., Heaton, D.C. & Spearing,
R.L. Trisomy 10 in acute myeloid leukemia: three new cases. Cancer Genet
Cytogenet 118, 148-50 (2000).
Drummond, M.W. & Spearing, R. Arterial thrombosis, GM-CSF, and
the lupus anticoagulant. Am J Hematol 64, 143 (2000).
Vuckovic, S., Fearnley, D.B., Gunningham, S., Spearing, R.L., Patton,
W.N. & Hart, D.N. Dendritic cells in chronic myelomonocytic leukaemia. Br
J Haematol 105, 974-85 (1999).
Scott, W.G., Scott, H.M., Henderson, S., Inder, A., Sanders, J., Spearing,
R., McArthur, C., Judson, J., Baker, B., Hicks, P. & Cotterell, P.
Cost comparison of antibacterial therapies for serious infections. A
New Zealand 3-hospital study. Pharmacoeconomics 16, 183-92 (1999).
Withington, S., Chambers, S.T., Beard, M.E., Inder, A., Allen, J.R.,
Ikram, R.B., Schousboe, M.I., Heaton, D.C., Spearing, R.I. & Hart,
D.N. Invasive aspergillosis in severely neutropenic patients over 18
years: impact of intranasal amphotericin B and HEPA filtration. J
Hosp Infect 38, 11-8 (1998).
Wickramasinghe, S.N., Spearing, R.L. & Hill, G.R. Congenital dyserythropoiesis
with intererythroblastic chromatin bridges and ultrastructurally-normal
erythroblast heterochromatin: a new disorder. Br J Haematol 103,
831-4 (1998).
Snowden, J.A., Hutchings, M., Spearing, R. & Patton, W.N. Acquired
high titre factor VIII inhibitor with underlying polyarteritis nodosa. Pathology 29,
221-3 (1997).
Reilly, J.T., Snowden, J.A., Spearing, R.L., Fitzgerald, P.M., Jones,
N., Watmore, A. & Potter, A. Cytogenetic abnormalities and their
prognostic significance in idiopathic myelofibrosis: a study of 106 cases. Br
J Haematol 98, 96-102 (1997).
Manley, R., Fearnley, D., Patton, W.N., Newhook, C., Spearing, R.L. & Hart,
D.N. Syngeneic peripheral blood stem cell transplantation for severe
aplastic anaemia. South Island Bone Marrow Transplant Team. Bone
Marrow Transplant 20, 1009-10 (1997).
Brennan, S.O., Hammonds, B., Spearing, R. & George, P.M. Electrospray
ionisation mass spectrometry facilitates detection of fibrinogen (Bbeta
14 Arg --> Cys) mutation in a family with thrombosis. Thromb Haemost 78,
1484-7 (1997).
Beard, M.E., Inder, A.B., Allen, J.R., Hart, D.N., Heaton, D.C. & Spearing,
R.L. The costs and benefits of bone marrow transplantation. NZ Med
J 104, 303-5 (1991).
Baker, B.W., Wilson, C.L., Davis, A.L., Spearing, R.L., Hart, D.N.,
Heaton, D.C. & Beard, M.E. Busulphan/cyclophosphamide conditioning
for bone marrow transplantation may lead to failure of hair regrowth. Bone
Marrow Transplant 7, 43-7 (1991).
Baker, B.W., Smith, M.P., Abbott, G.D., Beard, M.E., Spearing, R.L. & Heaton,
D.C. Aplastic anaemia in Christchurch Hospital 1979-89. NZ Med J 104,
468-70 (1991).
Spearing, R.L., Hickton, C.M., Sizeland, P., Hannah, A. & Bailey,
R.R. Quinine-induced disseminated intravascular coagulation. Lancet 336,
1535-7 (1990).
Phillips, J.K., Spearing, R.L., Davies, J.M., Hay, C.R., Parry, H.,
Nash, J.R. & Cawley, J.C. VIM-D salvage chemotherapy in Hodgkin's
disease. Cancer Chemother Pharmacol 27, 161-3 (1990).
Smith, S.R., Cheesbrough, J., Spearing, R. & Davies, J.M. Randomized
prospective study comparing vancomycin with teicoplanin in the treatment
of infections associated with Hickman catheters. Antimicrob Agents
Chemother 33, 1193-7 (1989).
Phillips, J.K. & Spearing, R.L. Resistant multiple myeloma treated
with mitozantrone in combination with vincristine and dexamethasone (MOD). Eur
J Haematol 40, 378-9 (1988).
Phillips, J.K., Spearing, R.L., Crome, D.J. & Davies, J.M. Gentamicin
volumes of distribution in patients with hematologic disorders. N
Engl J Med 319, 1290 (1988).
Spearing, R.L., Mackie, E.J. & Wright, J.G. Ventricular arrhythmias
despite an apparently correctly placed Hickman- Broviac catheter. Lancet 1,
924 (1987).
Spearing, R., Mackie, M.J., Risk, J.M., Johnson, P.M. & Bulmer,
J.N. Fetal and maternal uteroplacental leucocytes in aplastic anaemia.
Case report. Br J Obstet Gynaecol 93, 1163-5 (1986).
Spearing, R.L., Pamphilon, D.H. & Prentice, A.G. Pulmonary aspergillosis
in immunosuppressed patients with haematological malignancies. Q
J Med 59, 611-25 (1986).
McVerry, B.A., Spearing, R. & Smith, A. SLE anticoagulant: transient
inhibition by high dose immunoglobulin infusions. Br J Haematol 61,
579-80 (1985).
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